Background: Internet dependency has been associated to many harmful health effects to the modern life. Objective: This commentary briefly aims to identify the influence of anxiety in early phase of internet dependence of college students, and possible sociodemographic characteristics associated to this issue. Methods: We classified the internet dependency and anxiety levels of 293 college students by the Internet Addiction Test (IAT) and adapted Hamilton scale (HAM-D). Results: Anxiety increase 1.56 times the chance to be internet dependent. Students living in families with lower number of members are more dependent than students with more family members. Also, men were more anxious than women, which might deserve further attention. Discussion: Among other mental conditions anxiety might be treat in college students preventing the increase in internet abuse in this vulnerable population. It might be especially important, since currently, the world is handling with social isolation for COVID-19 prevention.